Micafungin

Лиофилизат By prescription

Antifungal drug of the echinocandins group

Micafungin

Important

Micafungin should be used only after careful assessment of the expected benefit and existing risk of therapy in patients with impaired liver function, in the presence of clinical and laboratory evidence of haemolysis or haemolytic anaemia. With caution, under careful clinical supervision and monitoring of plasma concentrations, micafungin should be used concomitantly with sirolimus, nifedipine.

Indications

Adults (including the elderly) and adolescents ≥ 16 years of age:
- Treatment of invasive candidiasis;

- treatment of oesophageal candidiasis in patients requiring intravenous administration of antifungal agents;

- prophylaxis of candidiasis in patients after allogeneic hematopoietic stem cell transplantation or in patients suspected of neutropenia (neutrophil count < 500/μL) for 10 days or more.

Children (including neonates) and adolescents < 16 years of age:
- Treatment of invasive candidiasis;

- prophylaxis of candidiasis in patients after allogeneic hematopoietic stem cell transplantation or in patients suspected of neutropenia (neutrophil count < 500/μL) for 10 days or more.

Contraindications

Hypersensitivity to or intolerance of micafungin, other echinocandins or any of the excipients.

Usage

It is administered intravenously in the form of infusion.

For the treatment of esophageal candidiasis — 150 mg/day.

For prophylaxis of candidiasis in patients after haematopoietic stem cell transplantation the dose is 50 mg/day.

Duration of use is established individually.

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