Ticagrelor
ТаблеткиA medicine to prevent stroke, heart attack and other conditions in people with acute coronary syndrome
Important
Indications
Ticagrelor is indicated for use together with acetylsalicylic acid (ASA) for the prevention of atherothrombotic complications:
- in adult patients with a history of myocardial infarction (myocardial infarction suffered 1 year or more ago) and high risk of atherothrombotic complications;
- in patients aged 50 years and older with coronary heart disease (CHD) and type 2 diabetes mellitus (DM2), without a history of myocardial infarction and/or stroke, who have undergone percutaneous coronary intervention (PCI).
Contraindications
Do not take the preparation Ticagrelor:
- If you are hypersensitive to Ticagrelor or other components of the preparation listed in point 6 of the leaflet;
- if you have pathological bleeding at the time of starting Ticagrelor;
- if you have a history of stroke caused by bleeding from the cerebral vessels;
- if you have severe liver failure;
- if you are taking any of the following medicines:
- ketoconazole (a drug to treat fungal infections);
- clarithromycin (a medicine to treat bacterial infections);
- nefazodone (a drug to treat depression);
- ritonavir or atazanavir (drugs to treat HIV and AIDS).
- If you are pregnant;
- if you are breastfeeding;
- if you are under 18 years of age.
Do not take Ticagrelor if any of the above applies to you. If you are not sure, talk to your doctor before taking this medicine.
Usage
Always use this medicine in full compliance with the recommendations of your doctor. If you have any doubts, consult your doctor.
Recommended dose
Before starting the drug Ticagrelor (in combination with ASC), patients should discontinue current antiaggregant therapy. Patients taking the drug Ticagrelor should receive daily, if there are no specific contraindications, a low maintenance dose of ASC (75-150 mg per day). When transferring patients from any prior antiaggregant therapy to Ticagrelor, the first dose should be administered within 24 hours of the last dose of another antiaggregant drug. You do not need to take a loading dose of Ticagrelor, the recommended dose is 60 mg 2 times a day (regardless of previous antiaggregant therapy and regardless of interruptions in therapy). Long-term therapy with the drug Ticagrelor is recommended, except for cases of clinical necessity in early withdrawal of the drug. There is no experience of using the drug Ticagrelor 60 mg for more than 3 years. Patients who started Ticagrelor 90 mg twice daily during treatment of acute coronary syndrome can continue therapy with Ticagrelor 60 mg twice daily without interruption after 1 year.
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Drugs in the category Cardiology
Has contraindications. Needs specialist overview.